August, 2025
August 2025
M T W T F S S
 123
45678910
11121314151617
18192021222324
25262728293031
Thor Halfdanarson: More on Genomics of Gastrointestinal NECs
Aug 20, 2025, 17:09

Thor Halfdanarson: More on Genomics of Gastrointestinal NECs

Thor Halfdanarson, Medical Oncologist at the Mayo Clinic, shared a post on X about a paper by T. Ozato et al. published in ESMO Gastrointestinal Oncology:

“More on genomics of NECs – nothing really new but nice lit addition nonetheless…

Repeat after me: Extrapulmonary NECs are not SCLC (and why do we assume SCLC chemo is the best…?).

APC, KRAS, BRAF, and FBXW mutations are very common in colorectal NECs

Should colorectal and pancreatic NECs be treated more like the adenocarcinoma arising in the same location? Trials like FOLFIRINEC will help address that question, right…?”

Title: Genomic heterogeneity and clinical implications in gastrointestinal neuroendocrine carcinoma: MYC and KRAS as predictive biomarkers

Authors: T. Ozato, Y. Kono, H. Yamamoto, A. Hirasawa, D. Ennishi, S. Tomida, S. Toyooka, M. Otsuka

You can read the Full Article on ESMO Gastrointestinal Oncology.

Thor Halfdanarson: More on Genomics of Gastrointestinal NECs

More posts featuring Thor Halfdanarson.