Anthony R. Sloan: Estrogen-Dependent Platelet PAR4 Signaling Shapes Immunity in Glioblastoma
Anthony R. Sloan, NCI National Research Service Award Postdoctoral Fellow at the Cleveland Clinic Lerner Research Institute, shared a post on X about a paper he co-authored with colleagues published in bioRxiv:
“We are happy to highlight a new preprint on bioRxiv where we reveal a sex-specific estrogen-dependent role for platelet PAR4 signaling in regulating CD8+ T cell immunity in glioblastoma.”
Title: Platelets drive immune suppression and glioblastoma growth in a sex-dependent manner via PAR4 signaling
Authors: Anthony R. Sloan, George Bukenya, Anu Aggarwal, Juyeun Lee, Daniel Rosaff, Tyler J. Alban, Ivan Juric, Daniel J. Silver, Liza Tack, Tanvi Navadgi, Natalie Reitz, Gavin P. Tannish, Xueer Yuan, Jesse Coker, Alliefair Scalise, Bhairavi Rajasekar, Alex Vincenti, Erin Mulkearns-Hubert, Craig M. Horbsinki, Andrew E. Sloan, Christopher G. Hubert, Jinquin Luo, Joshua B. Rubin, Evi X. Stavrou, Falk W. Lohoff, Marvin T. Nieman, Naseer Sangwan, Timothy A. Chan, Alok A. Khorana, Andrew Dhawan, Scott J. Cameron, Justin D. Lathia
You can read the Full Article on bioRxiv.
You can read more posts about Glioblastoma on OncoDaily.
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