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Jeffrey Dome: Promising Activity of Paclitaxel-based Treatment Regimens for Relapsed Wilms tumor
Aug 10, 2025, 11:01

Jeffrey Dome: Promising Activity of Paclitaxel-based Treatment Regimens for Relapsed Wilms tumor

Jeffrey Dome, Senior Vice President at Center for Cancer and Blood Disorders, Children’s National Hospital, shared a post by Children’s National Hospital, on LinkedIn, adding:

“We are excited to share these results that show promising activity of paclitaxel-based treatment regimens for relapsed Wilms tumor. Further research is needed, though these findings provide an additional treatment option for pediatric oncologists caring for patients with Wilms tumor that has returned after standard therapies.”

Quoting Children’s National Hospital‘s post:

“This new study shows promising results for paclitaxel-containing regimens in children with recurrent Wilms tumor. Among patients with measurable disease, 42.3% had a partial response and 15.3% had stable disease—for a clinical benefit rate of 57.6%.

“These findings provide an additional treatment option for pediatric oncologists caring for patients with recurrent Wilms tumor and merit prospective evaluations of paclitaxel-based regimens,” says Dr. Jeffrey Dome, corresponding author.”

Title: Anti-Tumor Activity of Paclitaxel-Containing Regimens in Recurrent/Refractory Wilms Tumor

Authors: Alissa Groisser, Amy Frantz, James I. Geller, Michael V. Ortiz, David Walterhouse, Mark Ranalli, Wendy Woods-Swafford, Peter Schoettler, Timothy Garrington, Elizabeth A. Mullen, Shifra Ash, Pooja Bardhan, Frank Balis, Jeffrey S. Dome

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Jeffrey Dome

Read More about Wilms Tumor on OncoDaily.

Jeffrey Dome: Promising Activity of Paclitaxel-based Treatment Regimens for Relapsed Wilms tumor