
Siddhartha Yadav: A Missed Opportunity for 7500 Patients With Metastatic Breast Cancer
Siddhartha Yadav, Breast and Gynecologic Oncologist in the Women’s Cancer Program at Mayo Clinic Comprehensive Cancer Center, shared a post on X about recent paper he and his colleagues co-authored published in JCO Precision Oncology:
“Despite clear guidelines, germline genetic testing remains underutilized in patients with metastatic breast cancer.
In our new study published in JCO Precision Oncology, we evaluated >15,000 patients with metastatic breast cancer and found that fewer than half received germline BRCA1/2 testing.
This represents a missed opportunity—not just for personalized treatment, but also for cancer prevention in families.
How can we close this gap?”
Title: Real-World Germline BRCA Testing, Poly(ADP-ribose) Polymerase Inhibitor Utilization, and Survival Outcomes in Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer
Authors: Siddhartha Yadav, Fergus J. Couch, Sam Hillman, Linlin Luo, Weiyan Li, Qixin Li, Jennifer Fallas Hayes, Jagadeswara R. Earla, Xiaoqing Xu
Read the Full Article on JCO Precision Oncology
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