Pat Soon-Shiong: The Relationship Between SARS-CoV and Cancer
Pat Soon-Shiong, Chairman of Chan Soon-Shiong Family Foundation, Executive Chairman ImmunityBio, Executive Chairman of Los Angeles Times, shared Harvard Epidemiology’s post on X, adding:
“The concern is that spike protein and TMPRSS2 are related biologically and can induce both immunosuppression and prostate cancer.
The relationship between spike and TMPRSS2 has been known since 2011.
Connecting the dots. Spike protein, viral persistence, reduction in p53, protease enzyme TMPRSS2, multiple cancer types – prostate, pancreas, colon… The need to clear the SARS-CoV virus / spike-protein-infected cells and address the science is critical”
Title: Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
Authors: Ilona Glowacka, Stephanie Bertram, Marcel A. Müller, Paul Allen, Elizabeth Soilleux, Susanne Pfefferle, Imke Steffen, Theodros Solomon Tsegaye, Yuxian He, Kerstin Gnirss, Daniela Niemeyer, Heike Schneider, Christian Drosten, Stefan Pöhlmann
Read the Full Article on Journal of Virology
“The multiple ways in which the virus enters the cells.”
Title: Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation
Authors: Bryan J. Fraser, Serap Beldar, Almagul Seitova, Ashley Hutchinson, Dhiraj Mannar, Yanjun Li, Daniel Kwon, Ruiyan Tan, Ryan P. Wilson, Karoline Leopold, Sriram Subramaniam, Levon Halabelian, Cheryl H. Arrowsmith, François Bénard
Read the Full Article on Nature Chemical Biology
Quoting Harvard Epidemiology’s post:
“New publication alert:
‘Etiology of prostate cancer with the TMPRSS2:ERG fusion: A systematic review of risk factors’ now in the International Journal of Cancer.”
Title: Etiology of prostate cancer with the TMPRSS2:ERG fusion: A systematic review of risk factors
Authors: Colleen B. McGrath, Alaina H. Shreves, Megan R. Shanahan, Hannah E. Guard, Manelisi V. Nhliziyo, Claire H. Pernar, Kathryn L. Penney, Tamara L. Lotan, Michelangelo Fiorentino, Lorelei A. Mucci, Konrad H. Stopsack
Read the Full Article on International Journal of Cancer
More posts featuring Pat Soon-Shiong.
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Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
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ESMO 2024 Congress
September 13-17, 2024
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ASCO Annual Meeting
May 30 - June 4, 2024
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Yvonne Award 2024
May 31, 2024
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OncoThon 2024, Online
Feb. 15, 2024
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Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023