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Sakditad Saowapa Shares ISTH 2025 Highlights on TPO-RAs and Chemotherapy-Induced Thrombocytopenia
Jun 23, 2025, 09:26

Sakditad Saowapa Shares ISTH 2025 Highlights on TPO-RAs and Chemotherapy-Induced Thrombocytopenia

Sakditad Saowapa, Oncologist at UI Holden Comprehensive Cancer Center, shared a post on X:

“ISTH 2025 Highlights.

Learned so much from the session “Thrombopoietin: A journey from bench to bedside” moderated by Dr. Manuel Carcao!

Key takeaways on TPO/TPO-RAs:

  • Role in CIT (Chemotherapy-Induced Thrombocytopenia)
  • Applications in AML, MDS, stem cell collection, liver disease, HCV
  • Emerging use of Hetrombopag
  • Improved platelet recovery
  • Reduced chemo delays
  • Higher dose intensity

Trials showed romiplostim and hetrombopag may significantly impact outcomes by preventing dose reductions and delays.

NCCN 2025 CIT guideline highlights:

  • Consider TPO-RA in platelet <100K for ≥3–4 weeks post-chemo
  • Romiplostim: 2–10 mcg/kg/week

Impressive science, powerful clinical relevance.”

Sakditad Saowapa Shares ISTH 2025 Highlights on TPO-RAs and Chemotherapy-Induced Thrombocytopenia

More posts featuring Sakditad “Tew” Saowapa.