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Khushali Jhaveri Shares Epcoritamab Combination Results in First-Line DLBCL
Jun 20, 2025, 16:26

Khushali Jhaveri Shares Epcoritamab Combination Results in First-Line DLBCL

Khushali Jhaveri, , shared a post on X:

“Bispecifics in the frontline?
In EPCORE NHL-5, Epcoritamab + pola-R-CHP in 1L DLBCL:
  •  ORR 100%, CRR 97%
  •  81% MRD– by C3D1 (ctDNA!)
Durable, deep responses. No ICANS. All CRS low grade.

Khushali Jhaveri Shares Epcoritamab Combination Results in First-Line DLBCL

Also: matched analysis of epco-R-miniCHOP vs R-miniCHOP shows 64% decreased risk of progression and 80% decreased risk of death.
CR rate: 92.8% vs 67.1%.
Small N, but a strong signal.”

Khushali Jhaveri Shares Epcoritamab Combination Results in First-Line DLBCL

Raul Cordoba, Chair of Community Stakeholder Committee at European Hematology Association (EHA), shared this post, adding:

“Impressive results!! We will need to wait for further follow-up to see the DoR. Great job!”

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