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NEJM Reports Phase 3 Trial on Omitting Nodal Irradiation in Node-Positive Breast Cancer
Photo: Depositphotos
Jun 6, 2025, 12:16

NEJM Reports Phase 3 Trial on Omitting Nodal Irradiation in Node-Positive Breast Cancer

NEJM shared a post on X:

“In women with node-positive breast cancer whose nodes became free of disease after neoadjuvant therapy, regional nodal irradiation did not reduce breast cancer recurrence or improve survival.

Full results from a phase 3 trial.”

NEJM Reports Phase 3 Trial on Omitting Nodal Irradiation in Node-Positive Breast Cancer

Omitting Regional Nodal Irradiation after Response to Neoadjuvant Chemotherapy.

Authors: Eleftherios P. Mamounas, Hanna Bandos, Julia R. White, Thomas B. Julian, Atif J. Khan, Simona F. Shaitelman, Mylin A. Torres, Frank A. Vicini, Patricia A. Ganz, Susan A. McCloskey, Peter C. Lucas, Nilendu Gupta, X. Allen Li, Beryl McCormick, Benjamin Smith, Rahul D. Tendulkar, Vivek S. Kavadi, Koji Matsumoto, Samantha Andrews Seaward, William J. Irvin, Jr., Jolinta Y. Lin, Robert W. Mutter, Thierry M. Muanza, Jannifer Stromberg, Reshma Jagsi, Anna C. Weiss, Walter J. Curran, Jr., and Norman Wolmark.

You can read the full article on The New England Journal of Medicine.

NEJM Reports Phase 3 Trial on Omitting Nodal Irradiation in Node-Positive Breast Cancer

More posts featuring NEJM.

Anna C. Weiss Atif J Khan Benjamin Smith Beryl McCormick Breast Cancer cancer Eleftherios P. Mamounas fight against cancer Frank A. Vicini Global fight against cancer Hanna Bandos Jannifer Stromberg Jolinta Y. Lin Jr. Julia R. White Koji Matsumoto Mylin A. Torres NEJM neoadjuvant chemotherapy neoadjuvant therapy Nilendu Gupta Nodal Irradiation Norman Wolmark OncoDaily Oncology Patricia A. Ganz Peter C. Lucas Rahul D. Tendulkar Reshma Jagsi Robert W. Mutter Samantha Andrews Seaward Simona F Shaitelman Susan A. McCloskey The New England Journal of Medicine. Thierry M. Muanza Thomas B. Julian Vivek S. Kavadi Walter J. Curran William J. Irvin X. Allen Li
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