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Ashraf Saad: Fenretinide Induces Cytotoxicity in GATA1+ Erythroid and Megakaryoblastic Leukemia
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May 18, 2025, 09:54

Ashraf Saad: Fenretinide Induces Cytotoxicity in GATA1+ Erythroid and Megakaryoblastic Leukemia

Ashraf Saad, pediatric hematologist, posted on X:

“”Here, we identify the small molecule (4-HPR, Fenretinide) as a novel GATA1 targeting agent in M6 and M7 AML cells…”
I believe it is tempting to test Fenretinide in ML-DS and get rid of chemo!”

Title: Fenretinide targets GATA1 to induce cytotoxicity in GATA1 positive Acute Erythroid and Acute Megakaryoblastic Leukemic cells

Authors: Yasharah Raza, Manal Elmasry, GuiQin Yu, Sam Blake Chiappone, Suhu Liu, Chiara Luberto

Ashraf Saad: Fenretinide Induces Cytotoxicity in GATA1+ Erythroid and Megakaryoblastic Leukemia

Ashraf Saad cancer Chiara Luberto GuiQin Yu Leukemia Manal Elmasry OncoDaily Oncology Sam Blake Chiappone Suhu Liu Yasharah Raza
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