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Chiara Corti: Decoding Clinical Trials in Metastatic Breast Cancer – Practical Insights for Optimal Therapy Sequencing
May 17, 2025, 17:38

Chiara Corti: Decoding Clinical Trials in Metastatic Breast Cancer – Practical Insights for Optimal Therapy Sequencing

Chiara Corti, Oncologist, Research Fellow at Dana-Farber Cancer Institute, shared a post on X:

“NEW ASCO EduBook chapter: Hope Rugo, Sara Tolaney, and I unpack some of the most debated trial design issues in m+ Breast Cancer—suboptimal control arms, crossover challenges, post-progression tx, non-inferiority margins, patient selection, and more.”

Title: Decoding Clinical Trials in Metastatic Breast Cancer: Practical Insights for Optimal Therapy Sequencing

Authors: Chiara Corti, Hope Rugo, Sara Tolaney

You can read the Full Article on ASCO Educational Book.

Chiara Corti: Decoding Clinical Trials in Metastatic Breast Cancer - Practical Insights for Optimal Therapy Sequencing

Bishal Gyawali, Associate Professor at Queen’s University, shared this post, adding:

“I don’t agree with the dismissal of the implications of SONIA and limiting SONIA results only to elderly and frail patients (that’s not SONIA’s population anyway) but am very happy to see these important issues of suboptimal control arms, crossover, post-progression treatments, NI margins etc being discussed.
We need more discussions about these issues in the broader oncology community. More open conversations about this. Enjoyed reading the paper even though I didn’t agree with some sections.”

More posts featuring Chiara Corti.