
Elvina Almuradova: From Dose-Finding to Dose-Optimization in Early-Phase Oncology Clinical Trials
Elvina Almuradova, Associate Professor of Oncology at the European Institute of Oncology (IEO), shared an article on LinkedIn:
“Excited to share our latest publication in Cancer Treatment Reviews: “From Dose-Finding to Dose-Optimization in Early-Phase Oncology Clinical Trials”.
We discuss the evolution from traditional dose-escalation (like 3+3) toward modern, model-based strategies that prioritize patient safety, biomarkers, and precision.
Grateful to my co-authors—and especially to Dr Dario Trapani and mentor Prof. Giuseppe Curigliano —for their invaluable support.”
From Dose-Finding to Dose-Optimization in Early-Phase oncology clinical trials.
Authors: Elvina Almuradova, Davide Izzo, Sara Gandini, Aurora Gaeta, Edoardo Giordano, Carmine Valenza, Gabriele Antonarelli, Dario Trapani, Giuseppe Curigliano.
You can Read the Full Article on Journal of Cancer Treatment Reviews.
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