Insight

Aruni Ghose: C the Signs supported over 235,000 cancer risk assessments – leading to 13,585 cancer diagnoses

Aruni Ghose/LinkedIn

May 2, 2025, 07:53

Aruni Ghose: C the Signs supported over 235,000 cancer risk assessments – leading to 13,585 cancer diagnoses

Aruni Ghose, Clinical Fellow at Barts Health NHS Trust, shared Bea Bakshi’s post on LinkedIn:

“C the Signs by my senior colleagues Dr Bea Bakshi, Miles Payling is a Game Changer in Primary Cancer Care – across 1,084 GP practices, C the Signs supported over 235,000 cancer risk assessments – leading to 13,585 cancer diagnoses, 20% more than the NHS average, while reducing urgent referrals by over 61,000!”

Quoting Bea Bakshi’s, Co-Founder and CEO at C the Signs, post:

“When we first began this journey in 2017, one of the most common questions we heard from system leaders was: If we help doctors identify more patients at risk of cancer, won’t we overwhelm the system? Would the NHS have the capacity to cope – even if the value to patients was clear?

At the time, referrals for suspected cancer were already rising rapidly year on year, without a corresponding improvement in detection rates. The prevailing belief was that more referrals equalled better detection – but we weren’t convinced that volume alone was the answer.

This week, we presented a real-world study on over 235,000 NHS patients at the American Association for Cancer Research Conference that speaks directly to that question.

The results mark a full-circle moment: across 1,084 GP practices, C the Signs supported over 235,000 cancer risk assessments – leading to 13,585 cancer diagnoses, 20% more than the NHS average, while reducing urgent referrals by over 61,000.

This is the power of AI-led triage: guiding the right patients to the right pathway at the right time – and just as critically, giving clinicians the confidence to safely reassure those who aren’t at risk.

This study reflects the journey we’ve been on for years: making early cancer detection safer, smarter, and more sustainable – for patients, clinicians, and the NHS. When we create solutions that work for both patients and health systems, we build technology that scales – and changes lives.

I’m incredibly grateful to all our NHS partners, ICBs, GP practices, and healthcare professionals who believed in the importance of investing in early detection in primary care – and in the shared truth that when we serve patients and healthcare professionals better, we strengthen the whole system.

The full paper, including health economic analysis, will be published soon in partnership with our NHS partners.”

More posts featuring Aruni Ghose on OncoDaily.