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Nirogacestat shows lasting benefits for desmoid tumors – ESMO
ESMO/LinkedIn
Mar 20, 2025, 08:31

Nirogacestat shows lasting benefits for desmoid tumors – ESMO

ESMO (European Society for Medical Oncology) shared a post on LinkedIn:

“In an updated analysis presented at ESMO Rare Cancers25, nirogacestat increased the objective response rate from 34.3% (for up to 1 year of treatment) to 45.7% (for up to 4 years of treatment) in patients with progressing Desmoid Tumours in the DeFi trial.

The incidence and severity of adverse events decreased after year 1. Real-world findings with nirogacestat were also presented from the DeNi study, which may help delineate which patients benefit most from treatment.

More results in the ESMO Daily Reporter.”

More posts featuring ESMO.

cancer DeFi trial Desmoid Tumours ESMO ESMO Rare Cancers25 European Society for Medical Oncology nirogacestat OncoDaily Oncology
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