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Mayo Clinic investigators identified proteins linked to immunotherapy resistance in mCRC – CRI

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Mar 16, 2025, 13:14

Mayo Clinic investigators identified proteins linked to immunotherapy resistance in mCRC – CRI

Cancer Research Institute (CRI) shared a post on LinkedIn about a paper by Bahar Saberzadeh-Ardestani et al. published in Clinical Cancer Research:

“In findings published in Clinical Cancer Research, Mayo Clinic investigators identified proteins linked to immunotherapy resistance in metastatic colorectal cancer.

Understand how this discovery could offer a step toward more personalized and effective colorectal cancer treatments, during March’s Colorectal Cancer Awareness Month.”

“Spatially resolved, multi-region proteomics for prediction of immunotherapy outcome in deficient mismatch repair metastatic colorectal cancer”

Authors: Bahar Saberzadeh-Ardestani, Zhenglong Liu, Mariam Stein, Will Sherman, Christy Trussoni, Charles Abbott, Dongyao Yan, Skyler Smith, Kandavel Shanmugam, Rondell Graham, Alos Diallo, Joshua Levy, Tamas Ordog, Frank Sinicrope.

Mayo Clinic investigators identified proteins linked to immunotherapy resistance in mCRC - CRI

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