Erman Akkus: DFS as surrogate for OS in neoadjuvant treatment of esophageal cancer
Feb 12, 2025, 08:58

Erman Akkus: DFS as surrogate for OS in neoadjuvant treatment of esophageal cancer

Erman Akkus, Medical Oncology Fellow at Ankara University, shared an article Nicolas Cabrit and colleagues authored on X:

“DFS as surrogate for OS in neoadjuvant treatment of esophageal cancer

Patient level

CS vs S: 0.73
CRS vs S: 0.76
CRS vs CS: 0.87

Trial level

CS vs S: 0.95
CRS vs S: 0.96
CRS vs CS: 0.93

PS: ORR did not seem to be a good surrogate in trials of GE cancers.”

Disease-free survival as surrogate for overall survival in esophageal cancer: an individual patient data meta-analysis of neoadjuvant chemotherapy and chemoradiotherapy

Authors: Nicolas Cabrit et al.

Erman Akkus: DFS as surrogate for OS in neoadjuvant treatment of esophageal cancer