Paolo Tarantino: Steroids are the mainstay for treating ADC-induced ILD

Paolo Tarantino shared a post on X by Sarah Sammons adding:

“Agree!

Steroids are the mainstay for treating ADC-induced ILD (but cause long-term toxicity)
Inhaled steroids are much better tolerated and provide benefit in RT-induced ILD + several other conditions (asthma, COVID)
Time to study them for preventing ADC-induced ILD!”

Quoting Sarah Sammons’s post below:

“We should try this either as primary or secondary prevention for T-Dxd pneumonitis…”

Source: Paolo Tarantino/X and Sarah Sammons/X

Dr. Paolo Tarantino, MD, is pursuing an advanced research fellowship at Dana-Farber Cancer Institute and Harvard Medical School, concurrently working towards a PhD in clinical research at the University of Milan. His research focuses on exploring the HER2 oncoprotein, investigating the emerging HER2-low subgroup of breast tumors, and developing novel antibody-drug conjugates targeting every subtype of breast cancer. With a  publication record exceeding 50 papers on breast cancer, he is recognized as a leading expert in the field.

Sarah Sammons is a medical oncologist at Dana-Farber’s Breast Oncology Center specializing in treating patients with all stages of breast cancer. She is particularly focusing on improving outcomes for those with metastatic breast cancer. Through leading numerous clinical trials, she has developed new treatment options for breast cancer patients. Additionally, Dr. Sammons is skilled in treating brain metastases.