Myeloma Paper of the Day, September 15th, suggested by Robert Orlowski
Robert Orlowski shared on X:
“Myeloma Paper of the Day: Case series of teclistamab for relapsed refractory myeloma in patients on dialysis finds 14/15 responded (2 sCRs, 2 CRs, and 7 VGPRs), median time to best response was 40 days, no median PFS yet with follow-up of 5.4 months.”
Source: Robert Orlowski/X
Teclistamab for relapsed refractory multiple myeloma patients on dialysis
Authors: P. Lebreton, F. Lachenal, S. Bouillie, G. M. Pica, H. Aftisse, L. Pascal, L. Montes, M. Macro, N. Johnson, S. Harel, M. Fernandez, B. De Renzis, B. Lioure, A. Lazareth, M. Javelot, C. Louni, A. Huart, A. Perrot.
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Robert Orlowski, M.D., Ph.D., holds multiple positions at The University of Texas , including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine. Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.
Dr. Orlowski’s expertise lies in both clinical practice and scientific research, with a particular focus on translating laboratory discoveries into effective treatments for patients. He investigates drug resistance mechanisms in myeloma and seeks to identify predictive biomarkers for treatment response. Notably, his past contributions include leadership roles in developing proteasome inhibitors like bortezomib and carfilzomib, as well as monoclonal antibodies such as daratumumab and elotuzumab.
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