Krishan Jethwa: LC-CRT vs. SC-RT for Rectal Cancer Organ Preservation

Krishan Jethwa, GI Radiation Oncologist at Mayo Clinic, shared a post on X about a recent paper by A. Bercz et al. published in Annals of Clinical Oncology.

“Organ preservation after neoadjuvant long-course chemoradiotherapy versus short-course radiotherapy”

Authors: A. Bercz, B.K. Park, E. Pappou, J.J. Smith, P.B. Romesser et al.

“LC-CRT vs. SC-RT for Rectal Cancer Organ Preservation

MSKCC SOC: LC-CRT TNT, during COVID shifted to SC-RT

Study demonstrated:

• cCR rates (~ 40%)
• OS and DFS
• Regrowth Organ Preservation with LC-CRT

Suggests LC-CRT preferred for NOM

German AIO-18 to clarify.”

Source: Krishan Jethwa/X