Joshua Fein: What’s the thinking on TBF regimen for CMML/MF overlap
Joshua Fein, Hematology-Oncology Fellow at Weill Cornell Medicine, shared a post on X about a paper titled “Full donor chimerism after allogeneic hematopoietic stem cells transplant for myelofibrosis: The role of the conditioning regimen” published in American Journal of Haematology.
Authors: Patrizia Chiusolo, Stefania Bregante, Sabrina Giammarco, Teresa Lamparelli, Lucia Casarino, Alida Dominietto, Anna Maria Raiola, Elisabetta Metafuni, Carmen Di Grazia, Francesca Gualandi, Federica Sora, Luca Laurenti, Simona Sica, Gianni Barosi, Fabio Guolo, Monica Rossi, Elena Rossi, Alessandro Vannucchi, Alessio Signori, Valerio De Stefano, Andrea Bacigalupo, Emanuele Angelucci.
“What’s the thinking on TBF regimen for CMML/MF overlap? There seemed to be a burst of TBF papers around 2020 for MF and I haven’t seen it mentioned much since. Anyone with experience using it for CMML?
Only with MTX/CNI/[ATG?] or extrapolate to PTCy?
- My typical disclaimer that I think there’s a special place in hell for CMML, what an awful disease.
- Hopefully MSD, presumably extrapolating to 7/8 + MTX/Tac/Aba is a bridge too far…”
Source: Joshua Fein/X