Jean-Charles Soria: Whole-genome sequencing of 2,023 samples sheds light on the molecular diversity of CRC

Jean-Charles Soria shared a post on LinkedIn:

“Colorectal cancer is not a single disease but a complex collection of subtypes with unique genomic landscapes.

Whole-genome sequencing of 2,023 samples sheds light on the molecular diversity of CRC.

Researchers identify 4 new subgroups of microsatellite-stable CRCs with distinct genomic features & prognostic associations”

The genomic landscape of 2,023 colorectal cancers

Authors: Alex J. Cornish, Andreas J. Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna, Boris Noyvert, Eszter Lakatos, Henry M. Wood, Steve Thorn, Richard Culliford, Claudia Arnedo-Pac, Jacob Househam, William Cross, Amit Sud, Philip Law, Maire Ni Leathlobhair, Aliah Hawari, Connor Woolley, Kitty Sherwood, Nathalie Feeley, Güler Gül, Juan Fernandez-Tajes, Luis Zapata, Ludmil B. Alexandrov, Nirupa Murugaesu, Alona Sosinsky, Jonathan Mitchell, Nuria Lopez-Bigas, Philip Quirke, David N. Church, Ian P. M. Tomlinson, Andrea Sottoriva, Trevor A. Graham, David C. Wedge, and Richard S. Houlston.

Source: Jean-Charles Soria/LinkedIn

Jean-Charles Soria serves as Amgen’s senior vice president of Oncology within Global Development. He is a medical oncologist and a professor of medicine at Paris-Saclay University. From 2017 to 2019, he was the senior vice president of Research and Development in Oncology at AstraZeneca. Additionally, Soria has authored or co-authored over 670 articles in leading international journals and has been recognized as one of the world’s most influential research scientists.