Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared on X:
”Myeloma Paper of the Day:
Immunoglobulin heavy chain constant domains may be promising targets for TCR-based cellular immunotherapy in myeloma and potentially other Ig-producing malignancies or autoantibody-mediated autoimmune diseases.”
Title: Immunoglobulin constant domains as targets for T-cell receptor-based treatment of multiple myeloma. Immunoglobulin constant domains as targets for T-cell receptor-based treatment of multiple myeloma
Authors: Miranda H. Meeuwsen, Anne K. Wouters, Johannes C. Wellershoff, Tassilo L. A. Wachsmann, Dennis F. G. Remst, Renate S. Hagedoorn, Michel G. D. Kester, Dirk M. van der Steen, Arnoud H. de Ru, Els P. van Hees, Masashi Matsuda, Fumihiko Ishikawa, Peter A. van Veelen, J. H. Frederik Falkenburg, and Mirjam H. M. Heemskerk.
You can read the full article on Blood Global Hematology.

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