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NEJM Reports Phase 3 Trial on Nodal Irradiation in Node-Positive Breast Cancer
Jun 6, 2025, 12:16

NEJM Reports Phase 3 Trial on Nodal Irradiation in Node-Positive Breast Cancer

NEJM shared a post on X:

“In women with node-positive breast cancer whose nodes became free of disease after neoadjuvant therapy, regional nodal irradiation did not reduce breast cancer recurrence or improve survival.

Full results from a phase 3 trial.”

NEJM Reports Phase 3 Trial on Nodal Irradiation in Node-Positive Breast Cancer

Omitting Regional Nodal Irradiation after Response to Neoadjuvant Chemotherapy.

Authors: Eleftherios P. Mamounas, Hanna Bandos, Julia R. White, Thomas B. Julian, Atif J. Khan, Simona F. Shaitelman, Mylin A. Torres, Frank A. Vicini, Patricia A. Ganz, Susan A. McCloskey, Peter C. Lucas, Nilendu Gupta, X. Allen Li, Beryl McCormick, Benjamin Smith, Rahul D. Tendulkar, Vivek S. Kavadi, Koji Matsumoto, Samantha Andrews Seaward, William J. Irvin, Jr., Jolinta Y. Lin, Robert W. Mutter, Thierry M. Muanza, Jannifer Stromberg, Reshma Jagsi, Anna C. Weiss, Walter J. Curran, Jr., and Norman Wolmark.

You can read the full article on The New England Journal of Medicine.

NEJM Reports Phase 3 Trial on Nodal Irradiation in Node-Positive Breast Cancer

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