Myeloma Paper of the Day, July 5th, Suggested by Robert Orlowski
Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Novel Cereblon variant with both exon 8 and 10 deletions in newly diagnosed and relapsed myeloma impacts interaction between CRBN with E3 ligase machinery and could have separate but likely additive effects on drug resistance.”
Title: A novel cereblon variant with both exon 8 and 10 deletions in newly diagnosed and relapsed multiple myeloma
Authors: Yuan Xiao Zhu, Soumya Dutta, Gregory J. Ahmann, Laura Bruins, Mariano Arribas, Xianfeng Chen, Abhigna Polavarapu, Jonathan Chapman, Isaac Lopez, Marta Chesi, P. Leif Bergsagel, Abhishek Singharoy, Rafael Fonseca, Lisa M. Rimsza.
You can read the Full Article in Blood Neoplasia.
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