Science

Apr 22, 2025, 09:14

Myeloma Paper of the Day, April 22nd, suggested by Robert Orlowski

Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:

“Myeloma Paper of the Day: Myeloma with 1q gain/amplification exhibits reduced CD38 expression via interleukin-6 receptor over-expression, and inhibition of the IL-6/JAK/STAT pathway by treatment with ruxolitinib or tocilizumab restores CD38 levels.”

“Multiple myeloma with 1q gain/amplification exhibits reduced CD38 expression via interleukin-6 receptor overexpression”

Authors: Wataru Kuroki, Akihiro Kitadate, Yuto Takahashi, Sayaka Iwama, Masahiro Yamada, Takahiro Kobayashi, Sho Ikeda, Kentaro Narita, Kosei Matsue, Naoto Takahashi.

More posts featuring Robert Orlowski.

Akihiro Kitadate cancer Kentaro Narita Kosei Matsue Masahiro Yamada multiple myeloma Myeloma Paper of the Day Naoto Takahashi OncoDaily Oncology Robert Orlowski Sayaka Iwama Sho Ikeda Takahiro Kobayashi Wataru Kuroki Yuto Takahashi

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