Hind Rafei, Assistant Professor at MD Anderson Cancer Center, shared a post on LinkedIn:
“What an extraordinary time to be in the field of engineered cell therapy!
I am incredibly excited to share our Review, published in Nature Reviews Immunology, A Guide to CAR T Cell Therapy, written with brilliant immunologists, Ranjan Upadhyay and Pam Sharma.
This Review is our attempt to tell the story of CAR T cells, from the decades of discoveries in T cell biology that made these therapies possible, through the engineering innovations that transformed them into life-saving treatments, to the clinical milestones, current challenges, and exciting opportunities that lie ahead. We also share our perspectives on several of the most important unanswered questions that we believe will shape the future of the field.
We were honored to dedicate this work to the memory of Zelig Eshhar, whose vision and pioneering work forever changed cancer immunotherapy and continues to inspire generations of scientists and physicians. A heartfelt thank you to Kirsty Minton and the outstanding editorial team at Nature Reviews Immunology for their guidance throughout this process.
As both a physician and scientist, I feel incredibly privileged to work in a field where fundamental immunology, bioengineering, and medicine come together with a single purpose: to bring better therapies to patients.
Here’s to the science, the collaboration, and to continuing our shared mission of making cancer history.”
Title: A guide to CAR T cell therapies: development, current status and future prospects
Authors: Hind Rafei, Ranjan Upadhyay, Padmanee Sharma
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