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Yakup Ergün: Denosumab and Zoledronic Acid in Advanced Breast Cancer patients
Yakup Ergün/X
May 20, 2025, 14:10

Yakup Ergün: Denosumab and Zoledronic Acid in Advanced Breast Cancer patients

Yakup Ergün, Medical Oncologist at Antalya City Hospital, shared an article on X:

“Zoledronic acid vs. Denosumab in HR+/HER2- aBC with bone mets + CDK4/6i.

PSM/IPTW-adjusted retrospective study.

ZA prolonged time to 1st SRE vs. DMAB.

No difference in PFS or OS between groups.

ZA might be preferred in this setting despite prior RCTs favoring DMAB?”

Comparative analysis of Denosumab and Zoledronic Acid in advanced breast cancer patients receiving CDK4/6 inhibitors.

Authors: Roberta Scafetta, Marco Donato, Carla Gullotta, Alessandra Guarino, Cristina Fiore, Luisana Sisca, Elena Speziale, Raffaella Troiano, Simone Foderaro, Valentina Ricozzi, Michele Iuliani, Sonia Simonetti, Silvia Cavaliere, Alessio Cortellini, Andrea Botticelli, Simone Scagnoli, Simona Pisegna, Carmen Criscitiello, Rebecca Pedersini, Caterina Sposetti, Elisa Tiberi, Giuliana D’Auria, Matteo Vergati, Marco Mazzotta, Roberta Caputo, Annarita Verrazzo, Maria Grazia Rossino, Federica Domati, Claudia Piombino, Francesca Sofia Di Lisa, Lorena Filomeno, Teresa Arcuri, Federica Puce, Federica Riva, Michela Palleschi, Marianna Sirico, Marta Piras, Luigia Stefania Stucci, Delia De Lisi, Paolo Orsaria, Edy Ippolito, Sara Ramella, Luca Visani, Niccolò Bertini, Ilaria Bonaparte, Stefania Gori, Luigi Rossi, Icro Meattini, Barbara Tagliaferri, Orazio Caffo, Ilaria Portarena, Azzurra Irelli, Elisabetta Cretella, Camillo Porta, Giampaolo Bianchini, Agnese Fabbri, Ugo De Giorgi, Patrizia Vici, Angela Toss, Ornella Garrone, Michelino De Laurentiis, Federica Villa, Rossana Berardi, Mauro Minelli, Claudio Vernieri, Giuseppe Curigliano, Bruno Vincenzi, Giuseppe Tonini, Daniele Santini, and Francesco Pantano.

You can read the full article on Journal of The Breast.

Yakup Ergün: Denosumab and Zoledronic Acid in Advanced Breast Cancer patients

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