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Aman Chauhan: Our Investigator initiated study of SVV plus Ipi-Nivo is all set to start
Jan 18, 2025, 08:31

Aman Chauhan: Our Investigator initiated study of SVV plus Ipi-Nivo is all set to start

Aman Chauhan, the leader of Neuroendocrine Cancer Program at Sylvester Comprehensive Cancer Center, posted on X:

“What a way to celebrate birthday. Got an amazing gift from FDA. Our Investigator initiated study of combination SVV plus Ipi-Nivo is all set to start. We will be enrolling high grade neuroendocrine cancer patients, a critical unmet need.

5 year of effort finally bearing fruits!!

Suggested reading: our work on SVV and its biomarker over the years.

  1. Abstract 6851: The genomic, transcriptomic, and immunologic landscape of TEM8 (ANTXR1) in neuroendocrine neoplasms (NENs)
  2. The genomic, transcriptomic, and immunologic landscape of TEM8 (ANTXR1) in small-cell lung cancer (SCLC).
  3. Oncolytic Seneca Valley Virus (SVV-001) Overcomes Checkpoint Inhibitor Resistance and Demonstrates a Systemic Anti-tumor Response in a Syngeneic Tumor Model
  4. TEM8 in Oncogenesis: Protein Biology, Pre-Clinical Agents, and Clinical Rationale
  5. Evolving role of seneca valley virus and its biomarker TEM8/ANTXR1 in cancer therapeutics
  6. Clinical Application of Oncolytic Viruses: A Systematic Review.

Aman Chauhan: Our Investigator initiated study of SVV plus Ipi-Nivo is all set to start

Dr. Aman Chauhan is the leader of Neuroendocrine Cancer Program at Sylvester Comprehensive Cancer Center and focuses on treating neuroendocrine tumors (NETs), including carcinoid tumors and high-grade neuroendocrine carcinomas. He is the national principal investigator for several investigator-initiated neuroendocrine cancer theranostics clinical trials. Dr. Chauhan serves on AJCC and ASCO NET guideline committees, and is an active member of the NANETS communication committee.