Adam Weiner, Urologic Oncologist at Cedars Sinai Medical Center, shared a post by National Cancer Institute on X, adding:
“Seems like just yesterday there were claims Viagra helped with another difficult disease.”
Quoting National Cancer Institute:
“Early research suggests that sildenafil, the erectile dysfunction drug commonly known as Viagra, may help stop cancer from spreading, not through its well-known effects on blood flow, but by disrupting how tumor cells manage cholesterol.”
Title: PDE5a Inhibition Restricts Cancer Metastasis by Disrupting NPC1-Mediated Cholesterol Trafficking Through a Non-canonical cGMP-Dependent Pathway
Authors: Yarden Ariav, Samah Hayek, Thomas Cantore, Neel Sanghvi, Lital N. Adler, Naama Darzi, Lipika R. Pal, David Robert Crawford, Tomer Malleron, Josh Silverbeck, Eliane Yardeni, Emma Hajaj, Efrat Ben-Zeev, Sanju Sinha, Shahar Ziman, Amir Shlomai, Sergey Malitsky, Maxim Itkin, Smadar Levin-Zaidman, Inna Goliand, Omer Goldman, Hila Tishler, Alexander Brandis, Tevie Mehlman, Yuri Kuznetsov, Noga Kozer, Karen Shamash, Ella Itzhaki, Neta Ben-Chaim Moskovits, Dean Ranmar, Salomon M. Stemmer, Shay Ben-Shachar, Eytan Ruppin, Ayelet Erez
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