Science

Nicholas Hornstein: DYNAMIC out now with 5 year data Stage II colon cancer

Nicholas Hornstein/X

Mar 11, 2025, 08:32

Nicholas Hornstein: DYNAMIC out now with 5 year data Stage II colon cancer

Nicholas Hornstein, Assistant Professor at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, shared an article by Jeanne Tie, et al. on X:

“DYNAMIC out now with 5 year data Stage II colon cancer using ctDNA adapted strategy.

Non-inferior statistically, but should note a clinically significant difference in outcomes among T4 patients (81% vs 70% RFS and 90% vs 80% OS). Have to question those NI margins…

Looks great on paper, but challenging to translate into clinical practice…”

Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer: 5-year outcomes of the randomized DYNAMIC trial.

Authors: Jeanne Tie, et al.

Nicholas Hornstein: DYNAMIC out now with 5 year data Stage II colon cancer

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