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Erman Akkus highlights new platinum derivatives Aurkine 16 and 18 for cancer treatment
May 8, 2025, 18:12

Erman Akkus highlights new platinum derivatives Aurkine 16 and 18 for cancer treatment

Erman Akkus, Medical Oncology Fellow at Ankara University, shared a post on X:

“New platinum derivatives ‘Aurkine 16 and 18’
  • Selectively target DNA in cancer cells
  • Both naïve and cisplatin-resistant CCA
  • Greater efficacy than cisplatin
  • No evident systemic toxicity
Potential to be a breakthrough, looking forward to clinical trials!”

Erman Akkus

Title: New platinum derivatives selectively cause double-strand DNA breaks and death in naïve and cisplatin-resistant cholangiocarcinomas

Journal: Journal of Hepatology

Authors: Irene Olaizola, Mikel Odriozola-Gimeno, Paula Olaizola, Francisco J. Caballero-Camino, Noelia Pastor-Toyos, Mireia Tena-Garitaonandia, Ainhoa Lapitz, Beatriz Val, Amanda R. Guimaraes, Maitane Asensio, Maider Huici-Izagirre, Colin Rae, David de Sancho, Xabier Lopez, Pedro M. Rodrigues, Elisa Herraez, Oscar Briz, Laura Izquierdo-Sanchez, Aitziber Eleta-Lopez, Alexander M. Bittner, Ana Martinez-Amesti, Teresa Miranda, Sumera I. Ilyas, Chiara Braconi, Maria J. Perugorria, Luis Bujanda, Iván Rivilla, Jose J.G. Marin, Fernando P. Cossio, Jesus M. Banales

Read the full article.

Erman Akkus

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