Tejas Patil, Thoracic oncologist CU Cancer Center, shared a post by Cancer Cell on X:
“Nice article that gets into why biomarkers like PDL1 and TMB aren’t always associated with ‘hot’ or ‘cold’ immune TME.”
Quoting Cancer Cell’s post:
“Online Now: Mutation burden and anti-PD-1 outcomes are not universally associated with immune cell infiltration or lymphoid activation.”
Authors: David Hsiehchen, Andrew Elliott, Joanne Xiu, Andreas Seeber, Wafik El-Deiry, Emmanuel S. Antonarakis, Stephanie L. Graff, Michael J. Hall, Hossein Borghaei, Dave S.B. Hoon, Stephen V. Liu, Patrick C. Ma, Rana R. McKay, Trisha Wise-Draper, John Marshall, George W. Sledge, David Spetzler, Hao Zhu
