E. Shyam P. Reddy/LinkedIn
Jun 27, 2025, 05:17
E. Shyam P. Reddy: Synthetic Protein Jams up Diseased Cells
E. Shyam P. Reddy, Professor and Director of the Cancer Biology Program at Morehouse School of Medicine, shared a post on LinkedIn:
“Synthetic protein jams up diseased cells
A synthetic ‘killswitch’ protein, just 17 amino acids long, can jam droplet-like structures that coordinate key cellular processes linked to cancer, viral replication, gene expression and more. The droplet-like structures have no membranes and help organize proteins and RNA molecules so that they can perform specific tasks efficiently and precisely.
The killswitch infiltrates the droplets and fixes them in place. In a pair of experiments, researchers found that the killswitch could reduce the proliferation of leukaemia cells in mice and also curtail the production of viral particles in infected cells.”
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