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Study led by Zhijian Qian points to strategy to overcome lung cancer drug resistance – UF Health Cancer Center
Apr 12, 2025, 13:54

Study led by Zhijian Qian points to strategy to overcome lung cancer drug resistance – UF Health Cancer Center

UF Health Cancer Center shared a post on LinkedIn:

“UF Health Cancer Center researchers have discovered a crucial mechanism by which a common gene mutation leads to chemotherapy resistance in non-small cell lung cancer.

Lung cancer is the deadliest cancer that presents a major burden in North Central Florida.

Led by Zhijian Qian, Ph.D., the Pierre Chagnon Professor of Cancer Research in the University of Florida College of Medicine, the findings suggest a novel therapeutic strategy involving drug inhibitors to reverse chemotherapy resistance.

The findings were published in The Journal of Clinical Investigation.

Read more in our latest research snapshot.”

Study led by Zhijian Qian points to strategy to overcome lung cancer drug resistance - UF Health Cancer Center

KRAS mutants confer platinum resistance by regulating ALKBH5 posttranslational modifications in lung cancer

Authors: Fang Yu, Zhijian Qian et al.

lung cancer