Louise Emmett: PSMA-PET Total Tumour Volume is Prognostic For Overall Survival in mCRPC
Louise Emmett, Nuclear Medicine and PET specialist at St Vincent’s Public Hospital Sydney, shared a post on X, about a recent article she and her colleagues co-authored, adding:
“PSMA-PET total tumour volume is prognostic for overall survival in mCRPC.
PSMA-PET value extends beyond selection for PSMA-RLT therapy in metastatic prostate cancer.”
Ian Davis, Professor of Medicine at Monash University and Eastern Health and Director and Chair of ANZUP, shared this post, adding:
“Third Lancet Oncology paper to come out of the ANZUP trials
Congratulations Louise Emmett and grateful thanks to all investigators, research teams, and of course the participants who have helped move the whole field ahead.”
Title: Prognostic and predictive value of baseline PSMA-PET total tumour volume and SUVmean in metastatic castration-resistant prostate cancer in ENZA-p (ANZUP1901): a substudy from a multicentre, open-label, randomised, phase 2 trial
Authors: Louise Emmett, Nathan Papa, Shalini Subramaniam, Megan Crumbaker, Andrew Nguyen, Anthony M. Joshua, Shahneen Sandhu, Andrew Weickhardt, Sze-Ting Lee, Siobhan Ng, Roslyn J. Francis, Jeffrey C. Goh, David A. Pattison, Thean Hsiang Tan, Ian D. Kirkwood, Narjess Ayati, Claire Niu, Michael S. Hofman, Andrew James Martin, Hayley Thomas, Ian D. Davis, Martin R. Stockler
Read the Full Article on The Lancet Oncology
Michael Hofman, Director of Prostate Cancer Theranostics and Imaging Centre of Excellence (ProSTIC) at Peter MacCallum Cancer Centre and co-author of the article, shared a post on X:
“A new PET biomarker in men with high-risk metastatic castration-resistant prostate cancer. Total tumor volume prognostic for overall survival and predictive for benefit of Lu-177 PSMA-617.
Great data from ANZUP, ENZA-P led by Louise Emmett.”
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