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Jad Chahoud
Jad Chahoud/moffitt.org

Jad Chahoud: Key Findings from 14-Year Follow-Up on Advanced Prostate Cancer

Jad Chahoud, Associate Member, Department of Genitourinary Oncology at Moffitt Cancer Center, shared on X about a recent paper by Emily Grist et al. published on Cell:

“In advanced Prostate Cancer, biology matters! ⁦⁦

14-year follow-up of >1,500 patients

  • Low AR signaling=poor outcomes
  • Decipher predicts benefit with docetaxel
  • PTEN loss → worse survival, docetaxel-sensitive

More info.”

Title: Tumor transcriptome-wide expression classifiers predict treatment sensitivity in advanced prostate cancers

Authors: Emily Grist, Peter Dutey-Magni, Marina A. Parry, Larissa Mendes, Ashwin Sachdeva, James A. Proudfoot, Anis A. Hamid, Mazlina Ismail, Sarah Howlett, Stefanie Friedrich, Lia DePaula Oliveira, Laura Murphy, Christopher Brawley, Oluwademilade Dairo, Sharanpreet Lall, Yang Liu, Daniel Wetterskog, Anna Wingate, Karolina Nowakowska, Leila Zakka, Claire L. Amos, Nafisah B. Atako, Victoria Wang, Hannah L. Rush, Robert J. Jones, Hing Leung, William R. Cross, Silke Gillessen, Chris C. Parker, Teresa Marafioti, Alfonso Urbanucci, Matthew Fittall, Edward M. Schaeffer, Daniel E. Spratt, David Waugh, Thomas Powles, Matthew R. Sydes, Felix Y. Feng, Daniel M. Berney, Mahesh K.B. Parmar, Noel W. Clarke, Elai Davicioni, Tamara L. Lotan, Christopher J. Sweeney, Louise C. Brown, Nicholas D. James, Gerhardt Attard.

Read the full article.

Jad Chahoud

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Alfonso Urbanucci Anis A. Hamid Anna Wingate Ashwin Sachdeva cancer Chris C. Parker Christopher Brawley Christopher J. Sweeney Claire L. Amos Daniel E Spratt Daniel M. Berney Daniel Wetterskog David Waugh Edward M. Schaeffer Elai Davicioni Emily Grist Felix Y. Feng Gerhardt Attard Hannah L. Rush Hing Leung Jad Chahoud James A. Proudfoot Karolina Nowakowska Larissa Mendes Laura Murphy Leila Zakka Lia DePaula Oliveira Louise C Brown Mahesh K.B. Parmar Marina A. Parry Matthew Fittall Matthew R. Sydes Mazlina Ismail Nafisah B. Atako Nicholas D. James Noel W. Clarke Oluwademilade Dairo OncoDaily Oncology Peter Dutey-Magni prostate cancer Robert J Jones Sarah Howlett Sharanpreet Lall Silke Gillessen Stefanie Friedrich Tamara L Lotan Teresa Marafioti Thomas Powles Victoria Wang William R. Cross Yang Liu