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Arndt Vogel: Shallow WGS of Circulating Tumour DNA Predicts Clinical Outcomes to Systemic Therapy in HCC
Arndt Vogel/aasld.org
Aug 2, 2025, 13:16

Arndt Vogel: Shallow WGS of Circulating Tumour DNA Predicts Clinical Outcomes to Systemic Therapy in HCC

Arndt Vogel, Head of the Center for Personalized Medicine, MHH at Hannover Medical School, shared a post on X about a recent article by Venkata Ramana Mallela et al. published in European Journal of Cancer:

“Shallow whole-genome sequencing of circulating tumour DNA predicts clinical outcomes to systemic therapy in HCC

  • sWGS enables evaluation of ctDNA
  • High TF and fragmentation associated with poor prognosis
  • TF predicts progression-free survival independently
  • promising prognostic biomarker”

Title: Shallow whole-genome sequencing of circulating tumour DNA predicts clinical outcomes to systemic therapy in advanced hepatocellular carcinoma

Authors: Venkata Ramana Mallela, Sultan N. Alharbi, Mathew Vithayathil, Caroline Ward, Rishi Patel, Rohini Sharma

Read the Full Article on European Journal of Cancer

Arndt Vogel: Shallow WGS of Circulating Tumour DNA Predicts Clinical Outcomes to Systemic Therapy in HCC

More posts featuring Arndt Vogel.

Arndt Vogel cancer Caroline Ward HCC Mathew Vithayathil OncoDaily Oncology Rishi Patel Rohini Sharma Sultan N. Alharbi Venkata Ramana Mallela
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