Aaron Goodman: Hydroxyurea for Sickle Cell Anemia

Aaron Goodman shared a post on X:

“Hydroxyurea for Sickle Cell Anemia!

Good stuff!

Mechanism

Increased HbF, decreased WBC, decreased RBC adherence to endothelium, increased RBC hydration = increased HbS polymerization and increased Nitric oxide.

Clinical results

Decreased RBC transfusion, decreased Hospitalization, decreased Pain episodes.

No increase in secondary malignancies!”

Aaron Goodman is a Hematologist/ Oncologist and an Associate Professor of Medicine at the University of California, San Diego. He is a member of the National Comprehensive Cancer Network (NCCN) guideline committee for both cutaneous NHLs and T-cell NHLs. Dr. Goodman is a well-known physician-scientist, educator, advocate, and social media influencer.