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Myeloma Paper of the Day, May 17th, suggested by Robert Orlowski
May 18, 2024, 03:23

Myeloma Paper of the Day, May 17th, suggested by Robert Orlowski

Robert Orlowski shared on X:

Myeloma Paper of the Day: Single cell multi-omic ATAC- and RNA-seq dataset links one plasma cell subtype with myeloma progression associated with chromosome 1q alterations, TP53 mutations, and higher expression of PHF19, an epigenetic regulator.”

Source: Robert Orlowski/X

1q amplification and PHF19 expressing high-risk cells are associated with relapsed/refractory multiple myeloma

Authors: Travis Johnson, Parvathi Sudha, Enze Liu, Nathan Becker, Sylvia Robertson, Patrick Blaney, Gareth Morgan, Vivek Chopra, Cedric Dos Santos, Michael Nixon, Kun Huang, Attaya Suvannasankha, Mohammad Abu Zaid, Rafat Abonour, and Brian Walker.

Myeloma Paper of the Day

Other insights by Robert Orlowski on OncoDaily.

Robert Orlowski holds multiple positions at The University of Texas MD Anderson Cancer Center, including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine. Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.