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Yu-Hung Wang: Loss of Dnmt3a increases self-renewal of JAK2V617F HSCs
Photo taken from Yu-Hung Wang/X
Mar 31, 2024, 09:02

Yu-Hung Wang: Loss of Dnmt3a increases self-renewal of JAK2V617F HSCs

Yu-Hung Wang, PhD student at The University of Manchester, shared on X/Twitter:

“Loss of Dnmt3a increases self-renewal of JAK2V617F HSCs and mitigates their attrition upon chronic pegIFNα Rx -A combination of pegIFNα and AZA can strongly decrease the JAK2-mut allele burden in MPN driven by JAK2V617F alone.”

Additional information.
Source: Yu-Hung Wang/X

cancer DNMT3A JAK2-mut allele JAK2V617F MPN OncoDaily Oncology pegIFNα Yu-Hung Wang
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