Gerry Hanna: Benefit of Hippocampal Avoidance in Whole Brain RT
Gerry Hanna, Marie Curie Chair of Clinical Oncology at Trinity College Dublin, shared on X:
“Showing the benefit of hippocampal avoidance in whole brain radiotherapy has been challenging
In this study in SCLC, HA during PCI decreased risk of overall neurocognitive toxicity with noninferior brain relapse risk and similar survival
Should this be a SOC?”
Title: Hippocampal Avoidance During Prophylactic Cranial Irradiation for Patients With Small Cell Lung Cancer: Randomized Phase II/III Trial NRG-CC003
Authors: Vinai Gondi, Stephanie L. Pugh, Minesh P. Mehta, Jeffrey S. Wefel, Wolfgang A. Tomé, Alexander Y. Sun, John Grecula, Kristin J. Redmond, Shannon Fogh, Laurie Gaspar, Andre Konski, Joseph Bovi, Clifford G. Robinson, Benjamin Corn, Gregory M. Videtic, Benjamin H. Lok, Harold A. Yoon, John H. Heinzerling, Albert S. DeNittis, Ronald C. McGarry, Kiran Devisetty, Vijayananda Kundapur, Abraham J. Wu, Edward C. McCarron, Isabelle Thibault, Edmund L. Simon, Andrew M. Baschnagel, Samir Narayan, Jondavid Pollock, Rebecca Paulus, Lisa A. Kachnic
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