![Jarushka Naidoo: Phase Ib Trial on Ivonescimab with Etoposide Plus Carboplatin in 1st line ES SCLC](https://oncodaily.com/pub/uploads/2024/09/Naidoo.jpg)
Jarushka Naidoo/X
Feb 11, 2025, 08:47
Jarushka Naidoo: Phase Ib Trial on Ivonescimab with Etoposide Plus Carboplatin in 1st line ES SCLC
Jarushka Naidoo, Full Professor of Medical Oncology at the Royal College of Surgeons in Ireland, shared a post on X about a recent paper by Zhiwei Chen et al. published in the Journal of Thoracic Oncology:
“Phase Ib Trial Ivonescimab (PD-1/VEGF bispecific)+Plt/Etop in 1L ES SCLC in Journal of Thoracic Oncology:
- Ivo (3 dose levels)+plt/etopx4 – ivo maintenance
- 35pts, ORR 80%, DCR 91%
- g3+ TRAEs 60% (low ANC, WBC, Hb)
Intriguing. VEGF is not a traditional SCLC target.”
Authors: Zhiwei Chen, Lin Wu, Qiming Wang, Xiao Xu, Shun Lu et al.
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