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Elisa Agostinetto: Drug-drug interactions between palbociclib and PPI in breast cancer
Jan 5, 2025, 18:21

Elisa Agostinetto: Drug-drug interactions between palbociclib and PPI in breast cancer

Elisa Agostinetto, Medical Research Fellow at the University Hospital of Brussels, shared a post on LinkedIn:

“What is the impact of drug-drug interactions between palbociclib and proton pump inhibitors (PPI) in breast cancer?

Can PPI use explain why the PALLAS trial was negative?

Now out in ESMO our analysis of PALLAS exploring this question.”

Drug-drug interactions between palbociclib and proton pump inhibitors in early breast cancer: an exploratory analysis of PALLAS (ABCSG-42/AFT-05/BIG-14-13/PrE0109)

Authors: E. Agostinetto, G. Pfeiler, D. Hlauschek, E.L. Mayer, M. Lambertini, E. de Azambuja, M. Bellet-Ezquerra, J.L. Meisel, G. Rubovszky, N. Zdenkowski, Y. Novik, M. Ruiz-Borrego, K.A. Gelmon, E.P. Mamounas, H. Iwata, D.R. Lu, L. Soelkner, C. Fesl, M. Gnant, A. DeMichele

Elisa Agostinetto: Drug-drug interactions between palbociclib and PPI in breast cancer