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Myeloma Paper of the Day, October 31st, suggested by Robert Orlowski
Oct 31, 2024, 15:16

Myeloma Paper of the Day, October 31st, suggested by Robert Orlowski

Robert Orlowski shared a post on X:

“Myeloma Paper of the Day: Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, shows encouraging pre-clinical activity in both in vitro and in vivo myeloma models alone and in combinations with BCMA bispecifics and CELMoDs.”

“Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, for the treatment of multiple myeloma”

Authors: Jan Eckmann, Tanja Fauti, Marlene Biehl, Christian Klein, Pablo Umaña et al.

Myeloma Paper of the Day, October 31st, suggested by Robert Orlowski

More posts featuring Robert Orlowski.

Robert Orlowski, M.D., Ph.D., holds multiple positions at The University of Texas MD Anderson Cancer Center, including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine. Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.

Dr. Orlowski’s expertise lies in both clinical practice and scientific research, with a particular focus on translating laboratory discoveries into effective treatments for patients. He investigates drug resistance mechanisms in myeloma and seeks to identify predictive biomarkers for treatment response. Notably, his past contributions include leadership roles in developing proteasome inhibitors like bortezomib and carfilzomib, as well as monoclonal antibodies such as daratumumab and elotuzumab.