Elvina Almuradova: Increased Breast Cancer Risk in Women with POI

Elvina Almuradova, Medical Oncologist Ambassador at European School of Oncology, shared a post on LinkedIn:

“Increased Breast Cancer Risk in Women with Primary Ovarian Insufficiency (POI)

-A recent study highlights an increased risk of breast cancer among women diagnosed with Primary Ovarian Insufficiency (POI).
– The majority of breast cancer cases were invasive ductal (93%) and estrogen receptor-positive (77%).
-28% never took HRT, and only 11% used HRT after age 50.
– Genetic testing in a small subset showed no pathogenic mutations, though one woman had a BRIP1 variant of uncertain significance.
– 89% of the women had a family history of various cancers.

This study underscores the importance of careful monitoring and personalized care for women with POI, particularly in terms of breast cancer risk.”

Source: Elvina Almuradova/LinkedIn

Breast Cancer Is Increased in Women With Primary Ovarian Insufficiency.

Authors: Kristina Allen-Brady, Barry Moore, Lauren E Verrilli, Margaret A Alvord, Marina Kern, Nicola Camp, Kristen Kelley, Joseph Letourneau, Lisa Cannon-Albright, Mark Yandell, Erica B Johnstone, and Corrine K Welt.