The National Cancer Institute Cancer Center Support Grant (CCSG) program provides major institutional support to NCI-Designated Cancer Centers and eligible institutions seeking NCI designation. The program strengthens the research infrastructure needed to integrate cancer research across basic laboratory science, clinical research, prevention, cancer control, and population science. (files.simpler.grants.gov)
CCSG funding can support scientific leadership, shared research resources, administration, strategic planning and evaluation, developmental funding, cancer research training and education coordination, community outreach and engagement, and centralized oversight of clinical research. The overarching goal is to create highly collaborative, interdisciplinary cancer research environments capable of accelerating discovery and translation into improved cancer prevention, diagnosis, and treatment. (files.simpler.grants.gov)
Eligibility Criteria:
- This is an institutional P30 award, not an individual investigator grant.
- Eligible applicant organizations include U.S. public and private institutions of higher education, nonprofit organizations, selected governmental organizations, and eligible for-profit institutions.
- Foreign/non-U.S. organizations are not eligible.
- For a new Clinical Cancer Center application, the institution must have at least $10 million per year in direct NIH cancer-focused research funding.
- For a new Basic Cancer Center application, the minimum NIH cancer-focused funding base is $6 million per year.
- Multiple PD/PI applications are permitted where appropriate.
Funding Details:
For new Type 1 applications, annual direct-cost limits depend on Cancer Center type:
- Basic Cancer Center: up to $1.2 million per year
- Clinical Cancer Center: up to $1.4 million per year
- Comprehensive Cancer Center: up to $1.5 million per year
Deadline:
- The NOFO uses recurring NIH submission dates through 2028.
- The next deadline is: September 25, 2026, at 5:00 PM local time of the applicant organization
- Scientific merit review: March 2027
- Advisory Council review: May 2027
- Earliest start date: July 2027
Further Information:
- Official opportunity listing: Visit the Simpler.Grants.gov Cancer Center Support Grants page for the current opportunity status, eligibility information, documents, and application details.
- Full NCI funding announcement: Review the official PAR-25-444 NOFO for detailed CCSG requirements, budgets, application components, and peer-review criteria.
- NCI Cancer Centers Program: Institutions considering a new CCSG application should consult the NCI Office of Cancer Centers regarding eligibility and calculation of the required cancer-focused research funding base.
- Application submission: Applications may be prepared through NIH ASSIST or an eligible institutional system-to-system solution and submitted through Grants.gov.
- Program contact: Questions may be directed to the NCI Office of Cancer Centers at ncicenters-r@mail.nih.gov. Funding Opportunity Number: PAR-25-444.