Horizon Europe Cancer Mission — Pragmatic Clinical Trials for Immunotherapy in Refractory Cancers (HORIZON-MISS-2026-02-CANCER-03)

Horizon Europe Cancer Mission — Pragmatic Clinical Trials for Immunotherapy in Refractory Cancers (HORIZON-MISS-2026-02-CANCER-03)

Due Date: 09/15/2026

This Horizon Europe Cancer Mission call funds large-scale, multinational, investigator-initiated pragmatic clinical trials to optimise immunotherapeutic interventions for patients with refractory cancers, with lung cancer explicitly named as a primary refractory cancer type and immunotherapy resistance as a flagship focus. Projects must incorporate real-world effectiveness and patient quality-of-life endpoints. The Cancer Mission has attracted particular interest in lung cancer immunotherapy from countries both within and outside Europe. This is a single-stage call with no two-step LOI process.

Eligibility Criteria:

  • Research consortia must comprise institutions in EU Member States or Horizon Europe Associated Countries (includes UK, Norway, Israel, Switzerland, and others)
  • At least one lead participant must be based in a Horizon Europe-associated country
  • Inclusion of clinical, academic, NGO, or industry partners is encouraged
  • No citizenship restrictions for researchers within eligible institutions
  • Projects must align with at least one Cancer Mission call topic

Funding Details:

  • Approximately €7–8 million per project for up to 3 projects
  • Covers research personnel, technology, consumables, and collaboration costs

Deadline:

  • September 15, 2026, 17:00 CET (single-stage submission; no LOI process)

Where to go for further information: