The National Cancer Institute (NCI) Research Opportunities in Cancer Epidemiology Cohort Studies U01 supports large-scale cohort research addressing important knowledge gaps in cancer etiology and survivorship.
Projects may use established cohorts, expand recently formed cohorts, or establish new cancer epidemiology cohorts, combining hypothesis-driven research with long-term follow-up, biospecimen collection, data sharing, and cohort infrastructure. Application budgets are not capped, and projects may receive support for up to five years.
Eligibility Criteria
- Eligible applicants include public and private institutions of higher education.
- Nonprofit organizations, with or without 501(c)(3) status, may apply.
- Foreign/non-U.S. organizations are eligible to apply.
- Non-U.S. components of U.S. organizations are also listed as eligible.
- Any investigator with the appropriate skills, knowledge, and resources may serve as PD/PI.
- Applicant organizations may submit multiple applications if each is scientifically distinct.
Funding Details
- Funding mechanism: U01 Research Project Cooperative Agreement.
- Budget: No fixed maximum; budgets must reflect the actual needs of the proposed project.
- Maximum project period: 5 years.
Deadline
- Opportunity posted: May 4, 2026.
- Applications open: September 5, 2026.
- First new-application deadline: October 5, 2026.
- First resubmission deadline: November 5, 2026.
- Earliest project start: July 2027.
- NOFO expiration: July 6, 2029.
Further Information
- The program supports research addressing gaps in cancer risk/etiology and outcomes among cancer survivors.
- Applicants may conduct hypothesis-driven research using an established cancer epidemiology cohort.
- Funding opportunity number: PAR-27-073.
- Official full announcement: View the PAR-27-073 Full Announcement
- Simpler.Grants.gov: View the funding opportunity
- Grants.gov: View on Grants.gov
- Program questions: ncidccpsegrpnofos@mail.nih.gov.