The Gilbert Family Foundation (GFF) Brain Tumor Initiative is requesting Letters of Intent for projects developing novel treatments for NF1-associated high-grade gliomas (HGAPs and GBMs). The goal is to accelerate transformative therapeutic strategies that can meaningfully impact disease progression and recurrence in neurofibromatosis type 1 (NF1) patients.
Eligibility Criteria:
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Principal Investigator must be an independent researcher at the level of Assistant Professor or above.
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Research must focus on NF1-associated high-grade gliomas (HGAPs or GBMs); sporadic GBM with NF1 loss considered if relevance is justified.
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Clinical trials are not eligible; projects must fall within lead optimization or development stages.
Funding Details:
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Up to $400,000 per year in direct research costs.
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Project duration: up to 5 years.
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Indirect costs allowed up to 10% of total direct costs (excluding travel and equipment).
Deadline:
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Letter of Intent Due: February 27, 2026 (5:00 PM ET).
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Full Proposal Due (invited applicants only): May 15, 2026 (5:00 PM ET).
Where to go for further information:
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Scientific contact: PoornimaVenkat@GilbertFamilyFoundation.org.
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Technical contact: carolinepoole@rock.com.