Jul 24, 2025, 07:57

Pragmatic Clinical Trials to Enhance the Quality of Life of Older Cancer Patients through Nutrition

This Horizon Europe Research & Innovation Action will fund academic, investigator-led pragmatic randomized or cluster-randomized trials of tailored nutritional care (optionally combined with physical activity or psychosocial support) integrated into routine oncology practice for patients aged 65 and over. Interventions must demonstrate improvements in survival, treatment outcomes, symptom relief and patient-reported quality of life, with full open-science data sharing via the future UNCAN.eu platform.

Eligibility Criteria:

Consortia of ≥ 3 independent legal entities from Member States or Associated Countries
Lead by academic clinical trial sponsors with access to older cancer patient populations
Inclusion of multidisciplinary stakeholders: oncologists, dietitians/nutritionists, behavioural scientists, patient representatives/caregivers, SMEs, insurers/charities, SSH experts, and health authorities
Design and run pragmatic (real-world) trials in routine care settings
Biological stratification and data disaggregation by sex, age, socio-economic status, ethnicity, etc.
Commitment to register datasets in the European Health Data Space catalogue and release tools/models under open-science principles via UNCAN.eu

Funding Details:

Action Type: HORIZON-RIA (Research & Innovation Action)
Total Budget: €15 000 000
Indicative Grants: 4 grants of €3 000 000–€5 000 000 each
Grant Model: Single-stage Horizon-AG (budget-based)

Deadline:

Submit via the EU Funding & Tenders Portal by 16 September 2025, 17:00 Brussels time.

Where to Apply & More Information:

EU Funding & Tenders Portal – search HORIZON-MISS-2025-02-CANCER-05
Horizon Europe Work Programme 2025 “Supporting the implementation of the Cancer Mission”
Horizon Europe Programme Guide and Online Manual