American Cancer Society Mission Boost Grants
The Mission Boost Grants (MBG) provide independent investigators with targeted “boost” resources to advance promising cancer therapies from preclinical stages (Stage I) through to human testing (Stage II), by funding milestone-driven risk‐reduction studies and early‐phase patient trials.
Eligibility Criteria:
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Stage I Mission Boost:
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U.S. academic institution or eligible non-profit affiliation
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Independent investigator with full-time faculty appointment (any career stage)
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Stage II Mission Boost:
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Same institutional and appointment requirements as Stage I
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Must have held a Stage I MBG for ≥18 months and completed all Stage I milestones
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Funding Details:
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Stage I Mission Boost:
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Duration: Up to 2 years
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Budget: Up to $135,000 USD/year direct costs + 10% indirect (total allowance $297,000)
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Stage II Mission Boost:
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Duration: Up to 18 months
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Budget: Up to $545,000 USD direct costs + 10% indirect
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Key Dates & Application Process:
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Deadlines: June 1, 2025 & December 1, 2025 (next business day if on weekend/holiday)
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How to Apply:
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Submit a Letter of Intent via ProposalCentral by the deadline.
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Invited applicants complete full proposal in ProposalCentral.
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Applications reviewed by ACS Scientific Advisory Committee.
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Milestone Requirement (Stage I): Define clear, outcome‐specific milestones to de-risk patient studies.
Primary Contact:
American Cancer Society Research Grants Office
[email protected]
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